Nanotube Coatings for Enhanced Medical Biosensors

“Nanotechnology coatings could lead to better brain implants (Nanowerk News) Biomedical and materials engineers at the University of Michigan have developed a nanotech coating for brain implants that helps the devices operate longer and could improve treatment for deafness, paralysis, blindness, epilepsy and Parkinson’s disease.” —-More

The present invention as disclosed in the U.S. patent application relates to biocompatible, biologically interfaced implantable devices capable of controlled bioactive substance delivery. The enhanced bioactive substance release is intimately coupled with probes and stimulation/sensing devices having effective three-dimensional integration into living tissue and other biological matrices for applications relating to neural prostheses, biosensors, targeted nanodelivery, and nanofiltration.

The disclosure further provides drug delivery devices, electrodes and sensors comprising one or more electrically conductive substrate in contact with a plurality of electrocontractile nanotubes. The nanotubes are coated on at least a portion of a conductive substrate. The nanotube comprises at least one opening and walls of conductive polymer defining a lumen therein. The lumen contains at least one bioactive substance. A power source can be connected to the conductive substrate(s) and provide a voltage to electrically actuate at least a portion of the nanotubes, causing the release of the bioactive substance from the nanotube through one or more openings by mass transport.

A patent application that is pending in the U.S. Patent & Trademark Office relates specifically to the above invention. This patent application along with select portions of the file wrapper of the pending case, including any actions by the patent examiner or response by applicants attorney, may be obtained from Patentfox. It will provide the reader with an in depth, detailed disclosure on advances in this leading edge technology that may not be fully exposed in other published literature.

PatentFox Posting No.: 7280
File size: 1 pdf file(s) totaling 2824 kb and about 75 pages.
Price: 20.00 USD

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